White Fang is a wolfdog who was born wild but becomes more dog-like after being domesticated by a Native American chief named Gray Beaver. Traveling through the Yukon Territory and the Northwest Territories, during the 1890s Klondike Gold Rush, White Fang struggles for survival. White Fang must overcome bouts of hunger, and survive attacks by a bulldog, a lynx, and several packs of wolves.
Much of White Fang is written from the viewpoint of the canine character, enabling London to explore how animals view their world and how they view humans. White Fang examines the violent world of wild animals and the equally violent world of humans. The book also explores complex themes including morality, conformity, and redemption.